Supplementary Figure 10: Identification of the MGE, LGE and CGE in E55 macaque monkey forebrain based on expression of Nkx2-1, COUP-TFII and Sp8.
From: Subcortical origins of human and monkey neocortical interneurons
(a–f) Nkx2-1 and COUP-TFII double-immunostained brain coronal sections spanning the rostral-caudal extent of E55 monkey brain. (g–i) Higher magnification of boxed areas in (c, d). Note that a small number of COUP–TFII+ cells in the dorsal MGE (g). (j–o) Sp8 and COUP-TFII double-immunostained E55 brain sections. Note that Sp8 was expressed in the cortical VZ in a high to low rostrodorsal to caudoventral gradient. (p–s) Higher magnification of boxed areas in (k, n, o). Note COUP-TFII+ cells in both the VZ and SVZ of the vCGE (s).
