Supplementary Figure 1: Identification of the dLGE/dCGE and vLGE based on expression of Sp8, Pax6 and Islet-1 in the human fetal brain at GW15. | Nature Neuroscience

Supplementary Figure 1: Identification of the dLGE/dCGE and vLGE based on expression of Sp8, Pax6 and Islet-1 in the human fetal brain at GW15.

From: Subcortical origins of human and monkey neocortical interneurons

Supplementary Figure 1

(a–d) Pax6 and Sp8 double-immunostained brain sections spanning the rostral-caudal extent of the brain at GW15. (e) Higher magnification of the boxed area in (c) showing that Pax6 was expressed in proliferative zones of the neocortex and dLGE. (f, g) Islet-1 and Sp8 double-immunostained GW15 human brain sections. (h) Higher magnification of the boxed area in (f) showing weakly Islet-1+ cells in the vLGE SVZ and strongly Islet-1+ cells in the striatum. LV, lateral ventricle; Sep, septum. St, striatum. Scale bars, 1 mm (a–d, f, g); 100 μm (e, h).

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