Supplementary Figure 2: Analysis of B-cell derivatives in the SEZ of p21-null 2-month old mice.
From: Transcriptional repression of Bmp2 by p21Waf1/Cip1 links quiescence to neural stem cell maintenance
(a) Immunohistochemistry for Mash1 (red) and Ki67 (green) in coronal sections through the SEZ of 2-m wild-type and Cdkn1a mutant mice, as seen by confocal microscopy. White arrows indicate double-positive cells. (b) Immunohistochemistry for βIII-tubulin (green) and Ki67 (red) in the SEZ of 2-m Cdkn1a wild-type and mutant mice. White arrows indicate double-positive cells. (c) Percentage of Mash1+ and βIII-tubulin+ cells and (d) Mash1-Ki67 and βIIItubulin-Ki67 double positive cells found in the SEZ of young animals of the two genotypes. Data are shown as mean values ± s.e.m. (n = 3); *p<0.05, **p<0.01. Scale bar in a: 10 μm; in b: 10 μm.
