Supplementary Figure 5: Null-direction light-evoked inhibitory postsynaptic potentials are dendritically generated.
From: Direction selectivity is computed by active dendritic integration in retinal ganglion cells
(a) Simultaneous dendritic (red trace, 245 μm from the soma) and somatic (black trace) recording of inhibitory postsynaptic potentials (IPSPs) evoked during the movement of null-direction light bars. (b) Overlain records show the large amplitude and fast kinetics of individual (thin traces) and averaged IPSPs (thick traces) at the dendritic recording site (red traces), and the attenuation and filtering of IPSPs as they spread to the soma (black traces). (c) The amplitude distribution of IPSPs at dendritic and somatic recording sites. The inset shows a cumulative probability distribution of the attenuation of dendritic IPSPs as they spread to the soma. Data have been pooled from n = 6 neurons, 427 events, dendritic recordings = 226 ± 20 μm from the soma.
