Supplementary Figure 4: Sensitivity-ordered tuning curves for odorant receptors.
From: The missense of smell: functional variability in the human odorant receptor repertoire
The y-axis represents the luciferase response normalized by Renilla Luciferase. The 55 odorants are displayed along the x-axis according to the strength of response they elicited from the reference allele of each receptor (defined as the most frequent allele that shows activity significantly higher than the vector control). If a given odorant did not significantly activate any of the variant receptors above the no-odor control (2-tailed t-test, α=0.05/55), that odorant's response was set to zero across all variants. The odors eliciting the strongest response are placed at the center of the distribution. The order of odorants is the same across all variants of a given receptor, but is different across receptors. Odorant information can be found in the linked source data file. Error bars represent standard error.
