Supplementary Figure 2: Re-expression of syt fully rescues normal synaptic transmission in syt KO neurons.
From: Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission
(a) Representative eEPSC traces recorded from WT neurons, and syt KO neurons that expressed WT syt cDNA, in the presence of 10 or 2 mM [Ca2+]o. (b) Scatter plots of the individual eEPSC amplitudes. For each condition, we recorded from 26 cells from a total of six coverslips, where two coverslips were obtained from each of three independent litters of mice. The mean values ± SEM are indicated. P-values, determined using a bootstrap approach, are indicated.
