Supplementary Figure 1: Distribution of MATR3 mutations detected in familial ALS patients.
From: Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
The upper panel shows the location of detected mutations and of the domains of MATR3 as determined by Hibino, Y., et al. Biochim. Biophys. Acta 1759, 195–207 (2006). Corresponding chromatograms showing mutant and wild-type alleles are as indicated, and conservation of amino acid residue across species is highlighted at the bottom (generated using the Clustal Omega online tool, www.ebi.ac.uk/Tools/msa/clustalo/).
