Supplementary Figure 1: Basic characterization of R6/2 mice. | Nature Neuroscience

Supplementary Figure 1: Basic characterization of R6/2 mice.

From: Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

Supplementary Figure 1

a-b. Nissl (cresyl violet) stained brain sections from WT and R6/2 mice at P30 (a) and P60 (b). Note, at P60, when R6/2 mice display HD-like symptoms, the volume of the caudate putamen (CP) is reduced leading to enlarged ventricles (V). c. Quantification of the reduced CP area in R6/2 mice relative to WT and P60. d. R6/2 mice weighed less than their WT littermates at P60. Significance was assessed with an unpaired Student's t test; p values are shown.

Back to article page