Supplementary Figure 6: Preservation of MeCP2 expression in GAD67- and PV-expressing interneurons in Mecp2Stop/y; Dlx5/6-Cre but not Mecp2Stop/y; Emx1-Cre mice.
From: Cellular origins of auditory event-related potential deficits in Rett syndrome
Representative images showing MeCP2 expression in cortex and its co-localization with GAD67 (a) or Parvalbumin (b). Scale bars correspond to 75 μm. MeCP2 immunoreactivity is absent from GAD67- and PV-expressing neurons in Mecp2Stop/y; Emx1-Cre mice. In contrast, MeCP2 expression is preserved in GAD67-and PV-expressing neurons in Mecp2Stop/y; Dlx5/6-Cre mice. These localization patterns were observed in three mice per genotype.
