Supplementary Figure 4: Fluorescence modulations during contingency degradation experiments
From: Volitional modulation of optically recorded calcium signals during neuroprosthetic learning
a. Mean fluorescence decreases in E1 cells during the contingency degradation manipulation. b. Mean ΔF/F is unchanged in E2 cells over the course of a normal training session (N=5 mice, 20 time points, p=0.234,t(18)=1.23). c. Mean ΔF/F is unchanged in E2 cells during the contingency degradation manipulation (N=5 mice, 20 time points, p=0.13,t(18)=−1.58). Together, these results suggest that animals primarily perform the task by modulating mean activity in E1 cells and do not coarsely modulate the mean activity of E2 cells. Error bars in all panels represent mean +/− SEM.
