Supplementary Figure 3: Ectopic spikes reset dendritic Ca2+ oscillations in LC neurons.
From: Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase
(a) Ectopic spikes induced by a short pulse of positive injection (2 nA, 1msec) resets the pacemaking cycle synchronized to dendritic Ca2+ transients. (b) After silencing an LC neuron with hyperpolarizing current, ectopic spikes can elicit dendritic Ca2+ transients. Data represents n=4 neurons from 4 mice.
