Supplementary Figure 2: Correlations between the 137 DMPs associated with NP pathology burden at P < 1.20 × 10–7 that were identified by De Jager et al., and our cross-cortex data. | Nature Neuroscience

Supplementary Figure 2: Correlations between the 137 DMPs associated with NP pathology burden at P < 1.20 × 10–7 that were identified by De Jager et al., and our cross-cortex data.

From: Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

Supplementary Figure 2

Neuropathology-associated DNA methylation scores for the top-ranked DMPs identified by De Jager and colleagues (X-axis)21 are strongly correlated (r = 0.49, P = 7.8E-10) with cross-cortex Braak-associated differences at the same probes in our samples (Y-axis). Abbreviations: DLFPC; Dorsolateral Prefrontal Cortex. Source Data is provided in the Supplementary Figure Source Data file.

Source data

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