Supplementary Figure 7: Loss of Sox10 does not result in an increase in white matter astrocytes | Nature Neuroscience

Supplementary Figure 7: Loss of Sox10 does not result in an increase in white matter astrocytes

From: Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes

Supplementary Figure 7

In the absence of Sox10 no change in the number of NKX6.1+/NFIA-expressing cells is observed (A-C, filled arrows). In addition, no difference was observed in the number of β-gal/NKX6.1 or β-gal/Pax6 WMAs in the absence of Sox10 (D-I, unfilled arrows). In C, F, I, “Het” corresponds to Sox10LacZ/+ and “KO” corresponds to Sox10LacZ/LacZ. Analysis of Ki-67 in Sox10LacZ/+ and Sox10LacZ/LacZ embryos did not reveal any changes in proliferation (J-L). All quantifications are derived from three embryos of each genotype from two independent litters.

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