Supplementary Figure 2: Comparison of cis-eQTL-based and expression-based clustering of gene expression | Nature Neuroscience

Supplementary Figure 2: Comparison of cis-eQTL-based and expression-based clustering of gene expression

From: Genetic variability in the regulation of gene expression in ten regions of the human brain

Supplementary Figure 2

Rows relate to expression IDs in all panels. (a) Heatplot depicting membership of each expression ID within each of the ten cis-eQTL clusters identified in Figure 1a (labelled according to the brain region it is most associated with). Expression IDs are ordered according to cis-eQTL-based clustering (as depicted in Figure 1a). (b) Heatplot depicting gene expression in all ten brain regions. Expression IDs are ordered according to cis-eQTL-based clustering (as depicted in Figure 1a). (c) Heatplot depicting membership of each expression ID within each of the ten cis-eQTL clusters identified in Figure 1a (labelled according to the brain region it is most associated with). Expression IDs are ordered according to expression-based clustering (as depicted in Figure 1b). (d) Heatplot depicting gene expression in all ten brain regions. Expression IDs are ordered according to expression-based clustering (as depicted in Figure 1b). CRBL: cerebellar cortex; FCTX: frontal cortex; TCTX: temporal cortex; HIPP: hippocampus; MEDU: the inferior olivary nucleus (sub-dissected from the medulla); OCTX: occipital cortex; PUTM: putamen (at the level of the anterior commissure); SNIG: substantia nigra; THAL: thalamus (at the level of the lateral geniculate nucleus); WHMT: intralobular white matter.

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