Supplementary Figure 5: Additional validation of AP-1 transcription factor ChIP-seq data | Nature Neuroscience

Supplementary Figure 5: Additional validation of AP-1 transcription factor ChIP-seq data

From: Genome-wide identification and characterization of functional neuronal activity–dependent enhancers

Supplementary Figure 5

(a) Aggregate plot of FOS ChIP-seq binding before and after 2h membrane depolarization at all FOS peaks called using MACS. Signal is shown for both anti-FOS antibodies (sc-52 and sc-7202). (b) Aggregate plot of FOS binding before and after membrane depolarization at all FOS binding sites. The effect of FOS shRNA infection on ChIP-seq signal at FOS binding sites is indicated from two biological replicates (sc-52 antibody). (c) Aggregate plot of FOSB and JUNB binding at all FOS binding sites

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