Supplementary Figure 11: Long-term stability of optical stimulation.
From: Tactile frequency discrimination is enhanced by circumventing neocortical adaptation
a Psychometric curves for detection of single light pulses at different time points after ChR2 expression. b, M50 values for all animals and hemispheres over the course of up to seven months after initial ChR2 expression. Although we observed some changes in required irradiance over time M50 values where mostly stable, indicating that our approach for cortical stimulation was suited for stable long-term application. Error bars show estimated 95% confidence intervals.
