Supplementary Figure 1: Differentially expressed genes in the microarray analyses.

a) Heat map diagram showing the expression levels of the differentially expressed genes from the comparison between NRG1 ICD infected DRG neurons and not infected (Limma moderated t–test P = <0.001; fold change cut off > 1.5 or < 0.66 df=6). N = 4 different biological replicates in each experimental condition. b) Venn diagram showing the number of differentially expressed genes in the comparisons tested in the microarray analyses (P = <0.01; fold change cut–off: 2). N = 4 different biological replicates in each experimental condition. c) RT–PCR on mRNA prepared from DRG neurons not infected, infected with a lentivirus expressing NRG1 ICD or EGFP as control. L–PGDS is upregulated only in neurons overexpressing NRG1 ICD. N = 3 different independent mRNA preparations and analyses.