Supplementary Figure 9: Estimated proportions of cell types within postmortem brain samples. | Nature Neuroscience

Supplementary Figure 9: Estimated proportions of cell types within postmortem brain samples.

From: Developmental regulation of human cortex transcription and its clinical relevance at single base resolution

Supplementary Figure 9

We utilized DNA methylation data to calculate the relative proportion of each cell type based on publicly available cellular populations, consisting of A) NeuN+ and B) NeuN- cells from primary tissue, and C) cell line data from ES-derived NPCs. We can correlate these composition estimates to the expression levels within identified differentially expressed regions (DERs) and the corresponding –log10(p-values) are shown in Panel D.

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