Supplementary Figure 3: Non-normalized (left) and normalized (right) temporal brain expression profiles for individual genes in the functional clusters of the implicated network.
From: Genotype to phenotype relationships in autism spectrum disorders
Human expression data were obtained from the HBT database. The individual panels in the figure represent profiles for: (a) postsynaptic density cluster genes, (b) chromatin modification and regulation cluster genes, (c) signaling and cytoskeleton cluster genes, and (d) channel activity cluster genes. Non-normalized profiles are shown in the left column. Every gene profile shown in the right column was normalized by dividing by the gene’s average expression value across all developmental stages. The colored lines in the right column show the average gene profile in each functional cluster. Vertical dashed lines separate prenatal and postnatal developmental stages. Error bars represent s.e.m.
