Supplementary Figure 11: Results are similar for neural selectivity measured using mutual information, area under ROC curve, and percent explained variance
From: Frequency-specific hippocampal-prefrontal interactions during associative learning
(a) Mean mutual information between spike counts and trial outcome (correct vs. incorrect) in PFC (top; n = 319) and HPC (bottom; n = 199) neurons, bias-corrected by subtracting trial-shuffled information. (b) Mean area under receiver operating characteristic (ROC) curve for discrimination of spike counts between correct and incorrect trial outcomes in PFC (top) and HPC (bottom) neurons, rectified around 0.5 and bias-corrected by subtracting trial-shuffled area-under-ROC values. Format for both plots is the same as for plots of neural percent explained variance in main text Fig. 3b. All three metrics show highly similar results—consistently showing greater selectivity in HPC than PFC—as we have observed for numerous neural activity contrasts.
