Supplementary Figure 5: Cyclin-dependent kinase 5 (CDK5) inhibition reprograms BTIC mitochondrial morphology.
From: Mitochondrial control by DRP1 in brain tumor initiating cells

a. Immunofluorescent staining of the mitochondrial marker TOM20 in 387 and 3565 BTICs treated with DMSO, Roscovitine or BMS-265246. b. Data are represented as mean ± s.e.m. (387: roscovitine: fragmented, p = 0.0041; tubular, p = 0.0010. 3565, roscovitine: fragmented, p = 0.0049; tubular: p = 0.0017 by Student’s t-test; n = 3).