Supplementary Figure 7: MeDIP and hMeDIP in MD3d adult mice.
From: Experience-dependent DNA methylation regulates plasticity in the developing visual cortex
MD3d in adult (p120) animals is not able to regulate DNA methylation (a) and hydroxylmethylation (b). MeDIP n = 6-7: ipsi ctx vs contra ctx, paired t- test, CRE1: t = 0.91, P = 0.4; CRE2-3: t = 0.51, P = 0.63; CRE4: t = 0.57, P = 0.53; BDNFex4-b: t = 0.73, P = 0.5; BDNFex4-c: t = 0.38, P = 0.72. hMeDIP: n = 6-8 ipsi ctx vs contra ctx, paired t-test, CRE1: t = 0.97, P = 0.37; CRE2-3: t = 0.02, P = 0.99; CRE4: t = 0.81, P = 0.44; BDNFex4-b: t = 0.92, P = 0.4; BDNFex4-c: t = 0.01, P = 0.99. Error bars represent SEM.
