Supplementary Figure 3: Morphological quantification of synaptic parameters and GluA1 endocytosis in cultured hippocampal neurons. | Nature Neuroscience

Supplementary Figure 3: Morphological quantification of synaptic parameters and GluA1 endocytosis in cultured hippocampal neurons.

From: Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses

Supplementary Figure 3

a-c, Summary graphs representing the absolute puncta quantification of GluA1, GluA2 VGluT1 and PSD95 density (a; GluA1: p = 0.694; GluA2: p = 0.714; PSD95: p = 0.819; vGluT1: p = 0.758), size (b; GluA1: p = 0.0213; GluA2: p = 0.0424; PSD95: p = 0.188; vGluT1: p = 0.421) and intensity (c; GluA1: p = 0.579; GluA2: p = 0.267; vGluT1: p = 0.796) in control and cre infected Nrxn3α/βcKO neurons.

d, Summary graph representing levels of GluA1 internalization normalized to the control condition (p = 0.0110).

Data shown represent means ± SEM. Data were collected from 5 independent experiments. Statistical significance was assessed by single-factor ANOVA.

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