Supplementary Figure 5: Characterization of burst and regular firing subicular neurons. | Nature Neuroscience

Supplementary Figure 5: Characterization of burst and regular firing subicular neurons.

From: Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses

Supplementary Figure 5

a & b, Sample traces of intrinsic spiking properties used to identify burst (a) and regular (b) firing subicular projection neurons. Postsynaptic subicular neurons were recorded in whole cell current clamp mode and currents steps were injected.

c & d, Summary graphs representing the passive membrane properties of burst (c; input resistance: p = 0.719; capacitance: p = 0.796) and regular (d; input resistance: p = 0.696; capacitance: p = 0.929) firing cells. Measurements were recorded from uninfected postsynaptic subicular neurons in Nrxn3α/β cKO slices that had been stereotactically injected with AAVs expressing GFP fused to inactive (control) or active (cre) cre-recombinase in the CA1 region of the intermediate hippocampus.

Data shown represent means ± SEM calculated from number of cells. Numbers in bar graphs represent number of cells/independent experiments. Statistical significance was assessed by single-factor ANOVA.

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