Supplementary Figure 1: Dose-dependent reversal of SNI-induced allodynia by intrathecal glial inhibitors in male but not female mice. | Nature Neuroscience

Supplementary Figure 1: Dose-dependent reversal of SNI-induced allodynia by intrathecal glial inhibitors in male but not female mice.

From: Different immune cells mediate mechanical pain hypersensitivity in male and female mice

Supplementary Figure 1

Reversal of SNI-induced allodynia by the glial inhibitors minocycline (MCL; a), fluorocitrate (FC; b) and propentofylline (PPF; c). Symbols represent mean ± SEM percentage of maximum possible anti-allodynia (see Methods); n=4–6 mice/dose/sex/drug. ANOVAs revealed significant main effects of sex in each case (MCL: F1,23 = 15.3, p=0.001; FC: F1,19 = 19.3, p<0.001; PPF: F1,26 = 66.7, p<0.001). ***p<0.001 compared to female mice.

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