Supplementary Figure 1: Normal granule cell excitability in Tc1 mice. | Nature Neuroscience

Supplementary Figure 1: Normal granule cell excitability in Tc1 mice.

From: Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome

Supplementary Figure 1

Pooled stimulus-response curves showing the mean ± SEM amplitude of antidromically-evoked compound action potential recorded in the granule cell (GC) layer of dentate gyrus (DG) vs. the strength of stimulation applied to mossy fibers in area CA3. Data are pooled from slices prepared from 7 wild-type (WT) and 6 Tc1 mice. Inset traces show example responses at 50, 150 and 300µA stimulation. Scale bar: 1ms, 5mV. P=0.70, F(1,11)=0.15, two-way mixed ANOVA.

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