Supplementary Figure 10: Event-locked analysis of hippocampal PAC after re-referencing hippocampal data against the most anterior (11 participants) or lateral (1 participant) contact on the same depth electrode. | Nature Neuroscience

Supplementary Figure 10: Event-locked analysis of hippocampal PAC after re-referencing hippocampal data against the most anterior (11 participants) or lateral (1 participant) contact on the same depth electrode.

From: Hierarchical nesting of slow oscillations, spindles and ripples in the human hippocampus during sleep

Supplementary Figure 10

(a) Contact used for re-referencing in a sample participant (red line). (b) Grand average unfiltered EEG trace across participants (mean ± s.e.m.) and (c) average of event-locked TFR (% change from pre-event baseline), locked to SO peak (left) and spindle trough (right). Spindle power (12–16 Hz) shows a significant increase vs. baseline from.25 to.75 s after SO peak (t(11) = 2.69, P = .021) and ripple power (80–100 Hz) shows a significant increase vs. baseline from –.25 to +.25 s around maximal spindle trough (t(11) = 4.00, P = .002). Spindle power (12–16 Hz) also showed a significant increase in the re-referenced data when aligning the TFR to the ripple center (as done in main text Fig. 4a, t(11) = 4.81, P <.001, –.25 to +.25 s around ripple center).

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