Supplementary Figure 11: Photo-suppression of L4 does not increase burst rate of L5 RS cells

a, Histogram of the fraction of high frequency spikes (see Methods) for L5 RS units with (red) and without (black) photo-suppression of L4 (p = 0.46, n = 75 units from 9 mice, Wilcoxon signed rank test). b, Scatter plot of the coefficient of variation of the inter-spike-intervals (ISIs) of L5 RS units with and without photo-suppression of L4 (light vs no light, p = 0.22, n = 75 units from 9 mice, Wilcoxon signed rank test). c, Histogram of the change in burst rate of L5 RS units during photo-suppression of L4 (p=0.67, n=75 units from 9 mice, Wilcoxon signed rank test). d, As in d) but for L5 RS units recorded in the visual cortex. e, As in c) but for V1 units. f, As in e) but for photo-suppression of SOM⁺ inhibitory neurons. g, As in f) but for SOM photo-suppression. In figure panels d), e) and g), burst rate was calculated using a Poisson surprise algorithm⁵³.