Supplementary Figure 3: Illumination of the cortex in mice expressing YFP alone shows no effect on the cortical response to sensory stimulation
From: A direct translaminar inhibitory circuit tunes cortical output
a, Left: Raster plot (top) and PSTH (bottom) of an example L5 RS unit during illumination of the cortex. Middle: Population PSTH under control conditions (black) and during illumination (red). Light had no effect on the spatial tuning curve of L5 RS units (p = 0.36, n =33 units from 3 mice, 2-way ANOVA, f(1) = 0.8445). b, As in a) but for L5 FS neurons (p = 0.7, n = 19 units from 3 mice, 2-way ANOVA, f(1) = 0.1108). c, As in a) but for L4 units (p = 0.5, n = 16 units from 3 mice, 2-way ANOVA, f(1) = 0.45). d, Scatter plot of neuronal firing rates of L5 RS units under control and photo-suppression conditions for their preferred tactile stimulus (n = 33 from 3 mice, p = 0.15, paired t-test). e, As in d) but for the non-contact condition (p = 0.62, paired t-test). f, Scatter plot of the spatial tuning index of L5 RS units under control and illumination conditions (p = 0.95, paired t-test).
