Supplementary Figure 6: Dopamine relationships to temporally-stretched model variables. | Nature Neuroscience

Supplementary Figure 6: Dopamine relationships to temporally-stretched model variables.

From: Mesolimbic dopamine signals the value of work

Supplementary Figure 6

(a) Kernel consisted of an exponential rise (to 50% of asymptote) and an exponential fall, with separate time constants. (b) Within-trial correlation coefficients between [DA] and kernel-convolved model variables V and δ, for a range of rise and fall time constants (0 – 1.5s each, in 50ms timesteps, using data from all 6 rats). Regardless of parameter values, [DA] correlations to V were always higher than to δ. (c) Same example data as Fig. 4E, but also showing convolved V and δ (using time constants that maximized correlation to [DA] in each case). (d) Trial-by-trial (top) and average (bottom) [DA], convolved V, and convolved δ, for the same session as Fig. 4d,e.

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