Supplementary Figure 4: The untreated DTA mice do not develop a late-onset clinical phenotype. | Nature Neuroscience

Supplementary Figure 4: The untreated DTA mice do not develop a late-onset clinical phenotype.

From: Oligodendrocyte death results in immune-mediated CNS demyelination

Supplementary Figure 4

(a-b) The untreated PLP/CreERT;ROSA26-eGFP-DTA (DTA w/o 4-HT) mice displayed normal coordination skills on the rotarod (a) and they did not show significant weight loss (b) as compared to control littermate (ROSA26-eGFP-DTA) mice during the time points that the tamoxifen-treated DTA mice were severely affected. Data are presented as the mean (± SEM), n= 5 mice/genotype for each data point shown in the graphs in a and b, p >0.05; two-way ANOVA with Bonferroni post-hoc analysis.

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