Supplementary Figure 3: Robustness of the parameters derived from the decision-making model | Nature Neuroscience

Supplementary Figure 3: Robustness of the parameters derived from the decision-making model

From: Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking

Supplementary Figure 3

(a) Comparison between transitions in the last two sessions (#9-10) displayed in the main part of the results, versus transitions measured two sessions before (#7-8). Transitions from these two data sets were not significantly different for all gambles (G1: T(18)=0.44, p=0.67; G2: T(18)=-1.36, p=0.19; G3: T(18)=-1.64, p=0.12, paired t-tests), indicating that the results are stable through the sessions, and that mice decisions reached steady state in this setting. (b, c, d) Proportions of exploitative choices (choice of the most valuable alternative) of the mice for the three gambles in different sets of reward probabilities: {25%, 50%, 75%} (b); {50%, 75%, 100%} (c); {25%, 75%, 100%} (d). (e) Parameters (ϕ and ß) derived from the model-based analysis (uncertainty model) of the transition functions, for the probabilities used in the main text (black) and in the present panels (b, green; c, purple; d, light blue). In each case the uncertainty-seeking parameter was significantly positive, showing that the parameters derived from the model provide a robust characterization (across probabilities sets) of the influence of uncertainty on decision-making process.

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