Supplementary Figure 6: Src mediated phosphorylation of Panx1 is Ca2+-independent. | Nature Neuroscience

Supplementary Figure 6: Src mediated phosphorylation of Panx1 is Ca2+-independent.

From: Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

Supplementary Figure 6

a&b) Co-immunoprecipitation assays (a) and quantification b) of phosphorylated Src and Panx1 in NMDAR complexes from hippocampal slices treated with excitotoxic NMDA/Glycine (100µM/10µM) in the presence of MK801 (20µM), BAPTA (100µM) or combined MK801/BAPTA application. **=p<0.01, ***=p<0.005 and ****=p<0.001 compared to unstimulated controls (lane 1). Full length blots are presented in supplementary figure 10.

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