Supplementary Figure 11: Circuit and potential mechanism of 4-Hz-mediated freezing behavior. | Nature Neuroscience

Supplementary Figure 11: Circuit and potential mechanism of 4-Hz-mediated freezing behavior.

From: 4-Hz oscillations synchronize prefrontal–amygdala circuits during fear behavior

Supplementary Figure 11

(a) During freezing behaviour, the preferential dmPFC to BLA coupling at 4 Hz allows the expression of conditioned fear behaviour through the recruitment of BLA circuits contacting the central amygdala (CE) which project to ventrolateral periaqueductal grey (vlPAG). (b), 4 Hz oscillations promote the cofiring of dmPFC and BLA neurons in the trough of the oscillation providing the conditions for fear expression.

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