Supplementary Figure 1: Model of magnetic activation via Magneto.
From: Genetically targeted magnetic control of the nervous system
(a) The cation channel, TRPV4, is gated by stretch (among other diverse classes of stimuli), to depolarize cells. For simplicity, only two of the four homomeric subunits are shown. (b) Coupling ferritin to the TRPV4 C-terminus converts TRPV4 to a magnetic field detector. Gating properties were extrapolated from published descriptions of TRPV1 and TRPA1 gating mechanisms48-50.
48. Cao et al. (2013) Nature 504, 113-118.
49. Liao et al. (2013) Nature 504, 107-112.
50. Paulsen et al. (2015) Nature 520, 511-517.
