Supplementary Figure 6: Two consecutive RNA loops to control neuronal conversion and maturation in HAFs.
From: Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells
The previously deduced PTB-miR-124-REST loop for neuronal conversion28 and the newly elucidated nPTB-miR-9-BRN2 loop for neuronal maturation. Each component of the loops likely regulates a set of downstream targets to generate specific neuronal phenotypes.
