Supplementary Figure 6: Zeb2 deletion does not lead to activation of BMP signaling in sciatic nerves
From: Zeb2 recruits HDAC–NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination
Immunoblot analysis of p-Smad (1/5/8) and Smad7 in sciatic nerves of control and Zeb2 cKO mutants at P14. No increase in p-Smad (1/5/8) or alteration of Smad7 was detected in in Zeb2 cKO sciatic nerves. The p-Smad level appears to be even reduced in Zeb2 cKO sciatic nerves. GAPDH was used as a loading control. n = 3 independent experiments. Full-length blots are presented in Supplementary Figure 10c.
