Supplementary Figure 8: Hippocampal molecular changes after memory reinstatement.
From: Infantile amnesia reflects a developmental critical period for hippocampal learning
Experimental schedule is shown above the panel. Densitometric western blot analyses of dorsal hippocampal total extracts obtained from rats trained (Tr) at PN17, 7 days later exposed to the reinstatement protocol [test (T1) and 2d later reminder shock (RS)] and euthanized 30min or 24 hours later. Data are expressed as mean percentage ± s.e.m. of rats trained at PN17, tested (T1) but not exposed to RS and euthanized at the matched time point [n=6/group, One–way ANOVA followed by Newman-Keuls Multiple Comparison Test, pTrkB F(2,17)= 0.27, P=0.77; GluN2A F(2,17)= 0.72, P=0.50; GluN2B F(2,17)= 0.08, P=0.82; 2 independent experiment). The numeric values are reported in Supplementary Table 15.
