Supplementary Figure 5: Enrichment of dURVs in schizophrenia cases across selected gene sets stratified per variant types and cohorts
From: Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia
Burden of dURVs across selected gene sets analyzed in this study stratified across disruptive and damaging URVs (left panel) and across previously analyzed exomes and newly available exomes (right panel). Enrichment and P values were computed using a logistic regression model using exome-wide dURV count as a covariate to correct for average exome-wide burden (dot-dashed line). Horizontal bars indicate 95% confidence intervals.
