Supplementary Figure 12: Ultra-rare variants counts relationships with population stratification | Nature Neuroscience

Supplementary Figure 12: Ultra-rare variants counts relationships with population stratification

From: Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

Supplementary Figure 12

Covariates within the Swedish exome cohort: (a) ultra-rare SNP and indel counts across cohort 12,334 individuals; (b) distribution of birth year across cohort individuals; (c) relationship of cohort individuals (in black) with 1000 Genomes project phase 1 individuals with respect to the first two principal components with removed outliers (in red); (d) relationship of cohort individuals with respect to the two main Swedish principal components; (e) relationship between principal components tracking Finnish ancestry and URV count; (f) relationship between principal components tracking Northern-Southern Swedish ancestry and URV count. Black crosses indicate individuals with less than or equal to 100 URVs detected, and red crosses indicate individuals with more than 100 URVs detected.

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