Supplementary Figure 10: Decorrelation of signal and noise.
From: Synaptic scaling rule preserves excitatory–inhibitory balance and salient neuronal network dynamics
(a) Signal correlation (for an input rate νstim = 5 Hz and a stimulus correlation Cstim = 0) of membrane potential vs holding potential. Isolated EPSPs (at -80 mV holding potential) or IPSPs (at 0 mV holding potential) were significantly more correlated than cPSPs (at ‑60 mV holding potential; n = 253 pairs in 56 preparations, paired Mann-Whitney U-test with a p-value 7×10-36 or 2×10-24 for EPSPs vs cPSPs or IPSPs vs cPSPs, respectively). (b) Correlation of inhibitory potential vs correlation of excitatory potentials. The grey line denotes the slope of unity passing through the origin (Pearson correlation coefficient between the two measures is 0.58, p = 6×10-24). (c) Same as a but for noise correlation. Isolated EPSPs or IPSPs were significantly more correlated than cPSPs (n = 253 pairs in 46 preparations, paired Mann-Whitney U-test with a p-value 4×10-20 or 2×10-7 for EPSPs vs cPSPs or IPSPs vs cPSPs, respectively). (d) Same as b but for noise correlation (the Pearson correlation coefficient is here 0.66, p = 8×10-33).
