Supplementary Figure 4: Pf synapses onto Purkinje cell dendrites in the presence of myelin | Nature Neuroscience

Supplementary Figure 4: Pf synapses onto Purkinje cell dendrites in the presence of myelin

From: A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination

Supplementary Figure 4

EM images of myelinated Pf in mutants at 1 year of age. The “en passant” synapses of Pf on Purkinje cells spines are restricted to nodal regions. Arrowheads point to presynaptic vesicles. M, myelin; Pf, parallel fiber axon; Pn, paranodal loop; s, dendritic spine. Images are representative of >3 similar experiments.

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