Supplementary Figure 12: Optogenetic activation of cholinergic fibers in mouse auditory cortex
From: Parallel processing by cortical inhibition enables context-dependent behavior
a, Overlay of LFP traces from 10 trials showing effect of optical stimulation. Blue bar: 5 sec period of laser stimulation. b, Amplitude spectra during 2 s before (gray) and during (black) stimulation, averaged from 10 optical stimulation trials. c, LFP spectrogram averaged from 10 trials, normalized by average power during pre-stimulation period. Blue bar: laser stimulation. d, Low-frequency power (1-10 Hz) was significantly decreased by optical stimulation of cholinergic fibers in auditory cortex (Pre-stim vs. During-stim, P < 0.01, Wilcoxon sign-rank test). Blue bar: laser stimulation. Interruptions in axes in d,e are periods of light-induced artifact on tungsten electrode.
