Supplementary Figure 8: Acoustic startle responses are intact in CNO-induced P0-Gi mice.
From: Developmentally defined forebrain circuits regulate appetitive and aversive olfactory learning
(a) Flowchart for acoustic startle testing of vehicle- and CNO- administered P0-Gi mice. (b) Dot plots of mean responses over seven days from 6 mice/group combined during pulse and prepulse noise presentations (26 recordings over 15 minutes; shaded areas define the pulse noise periods). (c) Dot plots of startle response presented as percent initial responses to train of Pulse Noises revealing that prepulse inhibition in both CNO- and vehicle-administered P0-Gi mice is intact. Lines are mean ± s.e.m. Significance determined by Mann-Whitney U test; mean ± s.e.m: vehicle, 72.4% ± 3.8%; CNO, 70.8% ± 7.4%; U=23.0, P=0.90; n=6 mice/group; n.s., not significant.
