Supplementary Figure 6: Ultrastructure of the sciatic nerve after unilateral CCI. | Nature Neuroscience

Supplementary Figure 6: Ultrastructure of the sciatic nerve after unilateral CCI.

From: Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity

Supplementary Figure 6

(a,d) Schematic drawings of the section plane. (b,c,e,f) High magnification of electron micrograph images of the ipsilateral (b,e) or contralateral side (c,f) proximal and distal to the ligation. (b,c) Proximal to the injury normal myelinated and unmyelinated nerve fibers with typical ultrastructure and intact myelin sheaths or Remak bundles are seen. (e,f) Distal to the injury strong demyelination and axonal degeneration were observed only ipsilateral to the injury. Scale bar = 2 μm, SC spinal cord, SN sciatic nerve.

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