Supplementary Figure 6: Frequency-dependent attenuation of EPSCs in PV interneurons in PV-Cre and NL3fl/PV-Cre mice. | Nature Neuroscience

Supplementary Figure 6: Frequency-dependent attenuation of EPSCs in PV interneurons in PV-Cre and NL3fl/PV-Cre mice.

From: Modulation of excitation on parvalbumin interneurons by neuroligin-3 regulates the hippocampal network

Supplementary Figure 6

a-b, EPSC amplitudes from individual cells in response to stimulation trains at increasing frequencies. Responses in PV-Cre (black) and NL3fl/PV-Cre (orange) cells for 2 Hz, 5 Hz, 10 Hz and 20 Hz stimulation (a) and for 30 Hz, 50 Hz, 100 Hz, and 200 Hz stimulation (b). c, Logarithmic graph showing the summary data from Fig. 4a, b, presented as mean ± SEM of synaptic summation (of EPSCs) as a function of the stimulation frequency (2-200 Hz) for stimuli 1-10 (left) and 10-20 (right). NL3fl/PV-Cre cells show a low pass filtering in the frequency dependent summation of EPSCs from 30 Hz upwards.

Back to article page