Supplementary Figure 2: Staining of endoderm, mesoderm and microglial differentiation markers and legend for IPA results. | Nature Neuroscience

Supplementary Figure 2: Staining of endoderm, mesoderm and microglial differentiation markers and legend for IPA results.

From: Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Supplementary Figure 2

(a) The endodermal markers SOX17 and FOXA2 were absent in the iPSC-neural cultures (CTR21) at day 60 of differentiation, but they were present in differentiated cultures of iPSC-endoderm (CTR33). (b) The microglial marker Iba1 was absent in day 60 iPSC-neural cultures, but present in wild-type mouse brain sections. Likewise, the mesodermal marker myosin was absent in day 60 iPSC-neural cultures, but present in sections of rat gastrocnemius muscle. (c) IPA gene symbols and relationships. IPA legend for gene networks and relationships/edges.

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