Supplementary Figure 6: Pressure ejection of agents onto capillaries did not directly stimulate upstream arterioles. | Nature Neuroscience

Supplementary Figure 6: Pressure ejection of agents onto capillaries did not directly stimulate upstream arterioles.

From: Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

Supplementary Figure 6

(A) Pipette positions (tip indicated by black arrowheads) for capillary stimulation (left) and arteriole stimulation (right). (B) Pressure ejection of 1 μM NS309 onto capillaries (P1, purple) had no effect on upstream arteriolar diameter, whereas direct arteriole stimulation (P2, orange) with this agent caused substantial dilation, indicating that solutions ejected onto capillaries do not spill over onto the arteriole.

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