Supplementary Figure 8: Summary of the impact of VT3Lbx1 or SOMLbx1 neuron ablation on Aβ inputs to I–IIo neurons, induced by nerve injury (SNI) | Nature Neuroscience

Supplementary Figure 8: Summary of the impact of VT3Lbx1 or SOMLbx1 neuron ablation on Aβ inputs to I–IIo neurons, induced by nerve injury (SNI)

From: Identification of spinal circuits involved in touch-evoked dynamic mechanical pain

Supplementary Figure 8

SNI opened Aβ inputs to I-IIo neurons in wild type control littermates (in comparison with “naïve” control mice without SNI). Note the selective loss of nerve injury-induced slow polysynaptic Aβ inputs to I-IIo neurons in VT3Lbx1-ablated mice (“VT3Lbx1 Abl”) following SNI, and loss of both fast and slow inputs in SOMLbx1-ablated mice (“SOMLbx1 Abl”) in comparison with control littermates with SNI.

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