Supplementary Figure 7: Disrupting retinal direction selectivity decreases the mean response amplitudes of posterior-motion-preferring cortical DS cells in FRMD7tm and starburst-ablated mice.
From: Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex
(a,d) Polar plots showing the normalized mean of the peak responses (Methods) of cortical DS cells in each of the stimulus directions in FRMD7tm and its control (a) and starburst-ablated and its control (d) mice. Cells with DSI > 0.5 are included in the plot. P denotes posterior, D dorsal, A anterior, V ventral motion direction in the visual field. (b,e) Top, normalized mean of the peak responses in posterior direction of motion in FRMD7tm and its control (b) and starburst-ablated and its control (e) mice. Dark curves show mean values, shaded areas show ±s.e.m around the means. Bottom, the logarithm of p values comparing the conditions using Fisher’s exact test. Values above the magenta line are non-significant. The DSI values shown along the horizontal axis denote the DSI thresholds defining cells as direction selective. (c,f) Top, horizontal versus vertical direction selectivity index computed from the normalized mean peak responses of cortical DS cells along horizontal and vertical directions in control and mutant mice (Methods). Bottom, the logarithm of p values comparing the conditions using Fisher’s exact test. Values above the magenta line are non-significant. The DSI values shown along the horizontal axis denote the DSI thresholds defining cells as direction selective.
